Ustad Vilayat Khan (28 August 1928 – 13 March 2004) was an Indian classical sitar player. Along with Imdad Khan, Enayat Khan, and Imrat Khan, he is credited with the creation and development of gayaki ang (an attempt to mimic the sound of the human voice) on the sitar.

He recorded his first 78-RPM disc at the age of 6, and gave his last concert in 2004 at the age of 75. He has composed the music for several films, including Jalsaghar (1958), The Guru (1969), and Kadambari (1976). He gave a chance to newcomer Kavita Krishnamurthy in Kadambari and it was the first song in her career.

Vilayat was born in Gouripur, Mymensingh in then East Bengal in British India and current Bangladesh. His father Enayat Khan was recognised as a leading sitar and surbahar (bass sitar) player of his time, as had been his grandfather, Imdad Khan, before him. He was taught in the family style, known as the Imdadkhani gharana by his father and other relatives in the family. Imdadkhani gharana is also called Etawah gharana known after a small city close to Agra where Imdad Khan lived. This family represents the sixthh generation of musicians that dates back to the Mughal Empire.