The Pinwheel Galaxy (also known as Messier 101, M101 or NGC 5457) is a face-on spiral galaxydistanced 21 million light-years (six megaparsecs) away from Earth in the constellation Ursa Major. First discovered by Pierre Méchain on March 27, 1781, it was communicated to Charles Messier who verified its position for inclusion in the Messier Catalogue as one of its final entries.

On February 28, 2006, NASA and the European Space Agency released a very detailed image of the Pinwheel Galaxy, which was the largest and most detailed image of a galaxy by Hubble Space Telescope at the time. The image was composed of 51 individual exposures, plus some extra ground-based photos.

On August 24, 2011, a Type Ia supernova, SN 2011fe, was discovered in M101.