Frank Rosolino (August 20, 1926 – November 26, 1978) was an American jazz trombonist.

Born in Detroit, Michigan, United States, Frank Rosolino studied the guitar with his father from the age of nine. He took up the trombone at age 14 while he was enrolled at Miller High School, where he played with Milt Jackson in the school’s stage band and small group. He did not graduate. He joined the 86th Division Army Band during World War II.

Following his time in the Army, he returned home to Detroit. He performed in the Mirror Ballroom or the Bluebird with other musicians, such as Kenny Burrell, Paul Chambers, Tommy Flanagan, and the Jones brothers, Hank, Thad, and Elvin). He played with Charlie Parker in the 3 Deuces on 52nd Street in New York City.