Major “Big Maceo” Merriweather (March 31, 1905 – February 23, 1953) was an American pianist and blues singer. He was mainly active in Chicago through the 1940s.

Born in Newnan, Georgia, he was a self-taught pianist. In the 1920s, he moved to Detroit, Michigan, to begin his music career. He moved to Chicago in 1941, where he made the acquaintance of Tampa Red. Red introduced him to Lester Melrose of RCA Victor and its subsidiary label Bluebird Records, who signed Merriweather to a recording contract. Merriweather suffered a stroke in 1946. He died of a heart attack on February 23, 1953, in Chicago and was interred at the Detroit Memorial Cemetery, in Warren, Michigan.