Dwike Mitchell (born Ivory Mitchell Jr.; February 14, 1930 – April 7, 2013) was an American piano player and teacher. He began his career as pianist for the Lionel Hampton Orchestra before joining Willie Ruff to form The Mitchell-Ruff Duo jazz group.

Mitchell joined the orchestra of the jazz musician Lionel Hampton. Hampton had heard Mitchell play at Lockbourne five years earlier and told him at the time that he wanted him as his pianist.Mitchell had abandoned his given name, Ivory, because of its popular association with piano keys. His new professional name, Dwike, was his mother’s suggestion, based on several family names.

In 1954 Mitchell was reunited with French horn player Willie Ruff, whom Mitchell had befriended when both were stationed at Lockbourne. Ruff had just received a master’s degree in music from Yale and was considering offers from two symphony orchestras. On television, he had seen Lionel Hampton’s orchestra perform on The Ed Sullivan Show and recognized Mitchell when the camera panned to the pianist. Ruff immediately phoned the television station, and in the ensuing conversation Mitchell convinced Ruff to abandon his symphony plans and instead join the Hampton orchestra.