Johnny St. Cyr (April 17, 1890 – June 17, 1966) was an American jazz banjoist and guitarist.

St. Cyr was born in New Orleans, Louisiana. He played for several leading New Orleans bands before moving to Chicago in 1923. He is most commonly remembered as a member of Louis Armstrong’s Hot Five and Hot Seven bands. He also played with Jelly Roll Morton‘s Red Hot Peppers. He composed the popular standard “Oriental Strut”, noted for its adventurous chord sequence.

From 1961 until his death in 1966, St. Cyr was the bandleader of the Young Men from New Orleans, who performed at Disneyland. He died in Los Angeles, California, and is buried in Evergreen Cemetery, in Los Angeles.