The most distant object easily visible to the unaided eye is M31, the great Andromeda Galaxy some two and a half million light-years away. But without a telescope, even this immense spiral galaxy – spanning over 200,000 light years – appears as a faint, nebulous cloud in the constellation Andromeda. In contrast, a bright yellow nucleus, dark winding dust lanes, expansive blue spiral arms and star clusters are recorded in this stunning telescopic image. While even casual skygazers are now inspired by the knowledge that there are many distant galaxies like M31, astronomers debated this fundamental concept 100 years ago. Were these “spiral nebulae” simply outlying components of our own Milky Way Galaxy or were they instead “island universes”, distant systems of stars comparable to the Milky Way itself? This question was central to the famousShapley-Curtis debate of 1920, which was later resolved by observations of M31 in favor of Andromeda, island universe.