NGC 4490, also known as the Cocoon Galaxy, is a barred spiral galaxy in the constellation Canes Venatici. It lies at a distance of 25 million light years from Earth. It interacts with its smaller companion NGC 4485 and as a result is a starburst galaxy. NGC 4490 and NGC 4485 are collectively known in the Atlas of Peculiar Galaxies as Arp 269. NGC 4490 is located 3/4° northwest of beta Canum Venaticorum and with apparent visual magnitude 9.8, can be observed with 15×100 binoculars. It is a member of Herschel 400 Catalogue. It belongs in Canes Venatici galaxy cloud II.

It was discovered by William Herschel in 1788. Two supernovae have been observed in NGC 4490, SN 1982F, and type II-P SN 2008ax, with peak magnitude 16.1