Vido William Musso (January 16, 1913 – January 9, 1982) was an American jazz saxophonist.

Musso moved with his family from Sicily to the U.S. in July 1920, having arrived at the Port of New York on the Italian steamship Patria. They lived in Detroit, where Musso started learning to play clarinet. Ten years later, he went to Los Angeles and formed a big band with Stan Kenton in 1935.Musso dropped out the next year to work with Gus Arnheim, Benny Goodman, and Gene Krupa. He accompanied Billie Holiday and pianist Teddy Wilson on recordings in the late 1930s. He replaced Bunny Berigan as the leader of his band and tried unsuccessfully at other times during the 1930s and 1940s to be a big band leader. But most of his career was spent as a sideman. After returning to Goodman, he was a member of big bands led by Harry James, Woody Herman, and Tommy Dorsey. He went back to play with Kenton during the middle 1940s. Having moved to California, he retired around 1975.