Claude Driskett Hopkins (August 24, 1903 – February 19, 1984) was an American jazz stride pianist and bandleader.

Claude Hopkins was born in Alexandria, Virginia, United States. Historians differ in respect of the actual date of his birth. His parents were on the faculty of Howard University. A talented stride piano player and arranger, he left home at the age of 21 to become a sideman with the Wilbur Sweatman Orchestra, but stayed less than a year. In 1925, he left for Europe as the musical director of The Revue Negre which starred Josephine Baker with Sidney Bechet in the band.